This work articulates the main problems and questions that arise at the intersection of new materialism and theology. The text is divided into three parts. Part 1 provides some introductory definitions and historical context for understanding the relationship between new materialism and theology. Part 2 examines the novelty and materiality in new materialism, questioning both categories, while enumerating very new and quite material challenges that new materialism poses to theology. The concluding part considers the theological implications and material possibilities of technological developments for facilitating posthuman or transhuman futures.